Phosphodiesterase 5 (PDE5) inhibitors are medications that can influence blood flow and cellular communication in the body. PDE5 inhibitors may also appear in some foods and supplements.
People can take PDE5 inhibitors to manage conditions such as erectile dysfunction (ED) or pulmonary hypertension.
One of the methods to treat erectile dysfunction is to use drugs that inhibit the PDE-5 hormone. Yes, there are pills like Cialis, Cenforce and Kamagra that help you fight erectile dysfunction.
With proper care and the use of erectile dysfunction medications, some forms of early-stage erectile dysfunction can be completely cured.
What are PDE5 inhibitors?
PDE5 is an enzyme present in the walls of blood vessels. This affects blood flow and how cells signal in the body.
PDE5 inhibitors work by blocking the PDE5 enzyme, which relaxes blood vessels and increases blood flow.
People can take PDE5 inhibitors to treat erectile dysfunction or pulmonary hypertension.
In people with erectile dysfunction, PDE5 inhibitors increase blood flow to the penis, thus improving erectile function.
In people with pulmonary hypertension, PDE5 inhibitors may help:
- Control blood flow to the arteries of the lungs
- Increased blood flow to the lungs
- Low blood pressure
Research also suggests that PDE5 inhibitors may have potential therapeutic effects for conditions such as heart disease, diabetes, and cancer.
Types of PDE5 inhibitors
Erectile dysfunction can be caused by psychological or physiological factors. PDE5 inhibitors are only effective in treating erectile dysfunction caused by physiological factors.
Psychotherapy or counseling are treatment options for psychological causes of erectile dysfunction, such as stress or anxiety.
The four main types of PDE5 inhibitors available include:
- Sildenafil (Viagra)
- Tadalafil (Cialis)
- Vardenafil (Levitra or Staxyn)
- Avanafil (Stendra)
How do PDE-5 inhibitors treat erectile dysfunction?
Let’s try to understand how PDE-5 hormone inhibitor drugs treat erectile dysfunction.
It all starts from the moment you take an erectile dysfunction drug like Fildena.
Now, this generic drug, as you know, will begin its suppressive action on PDE-5 hormones as soon as it takes effect.
Within minutes the action of the PDE-5 hormone ceases to exist. When you reach this stage, your body secretes a hormone called GMP hormone or guanosine monophosphate hormone.
This hormone is unstable and quickly stabilizes in its cyclic form which is the hormone cGMP or cyclic guanosine monophosphate.
When levels of the hormone cGMP exceed a threshold, it can trigger the vasodilatory effect of nitric oxide.
Nitric oxide, present in trace amounts in our body, begins to relax the tissues of the blood vessels.
When blood vessels and arteries begin to relax, the surface area inside them increases.
This is how blood flow increases in just a few minutes. When the two important tissues of your penis are filled with more blood, it helps the man achieve the desired hardness of his erections.
Can PDE-5 inhibitor drugs completely cure my erectile dysfunction?
So far, the process, but can PDE-5 hormone inhibitor drugs containing generic Kamagra oral jelly completely cure my erectile dysfunction?
As we mentioned at the beginning of this article, the cure for erectile dysfunction with the help of drugs will entirely depend on this.
In some cases, you can get very positive results, and over time, you can even start having strong erections on your own, without using erectile dysfunction drugs.
But in other cases, it can also lead to mild results in more severe cases of erectile dysfunction.
But it also considers the initial cause of erectile dysfunction. You see, sometimes erectile dysfunction is a congenital problem and is called impotence.
But in other cases, it is usually the cause of some existing physical or psychological problems. Ask your doctor to find more relevant information on this topic.
What precautions should you take when using PDE-5 hormone inhibitors?
Someone who is better prepared to deal with the side effects of PDE-5 inhibitor drugs like Cenforce has a good idea of the precautions to follow.
In any case, we have highlighted them below for your reference.
- Do not take any overdose
- Do not suddenly change the dose
- Avoid cases of missed doses
- Do not take contraindicated drugs or non-medicinal substances
Side effects
Of course, there are some side effects that you need to watch out for when using drugs like Vidalista. Patients should have an idea of the following side effects of drugs that inhibit the PDE-5 hormone-
- Heachache
- Diarrhea
- Skin rashes
- Itching
- Vomit
- Nausea
- Dizziness
- Stomach cramps
- Blurred vision
- Chest pain
Final Word
PDE5 inhibitors block PDE5, an enzyme found in the walls of blood vessels. Blocking PDE5 causes blood vessels to relax, increasing blood flow to certain areas of the body.
This effect means they can help manage conditions such as erectile dysfunction and pulmonary hypertension.
People who are taking nitrate medications should avoid PDE5 inhibitors because the combination of drugs can lead to a dangerous and potentially life-threatening drop in blood pressure.
Other medications, foods, supplements, or herbal remedies may contain PDE5 inhibitors. These may not be subject to FDA regulations and contain unlisted ingredients or contaminants or interact with other drugs.
Before taking PDE5 inhibitors, individuals should consult their doctor to discuss any potential side effects or drug interactions associated with these medications.
